Free download Advances in Metallic Biomaterials By Mitsuo Niinomi

Tissues, Materials and Biological Reactions

Authors of:  Advances in Metallic Biomaterials By Mitsuo Niinomi

Mitsuo Niinomi

Takayuki Narushima

Masaaki Nakai

Table of Contents in Advances in Metallic Biomaterials By Mitsuo Niinomi

Part I: Biological Tissues and Organs  

This section delves into the intricate structures and functions of biological tissues and organs, as well as their relevance in medical applications. It explores the interplay between the natural biological environment and engineered biomaterials.

1. Takayoshi Nakano examines how the unique anisotropic (directionally dependent) microstructure of bone tissue influences its mechanical properties. The chapter emphasizes the need for biomaterial designs that mimic these properties to enhance compatibility and functionality in medical applications.

2. Takashi Sakai provides an in-depth look at the anatomy and physiology of human joints. This chapter explains their normal functions and discusses various pathological conditions that can impair joint performance, highlighting the significance of advancements in biomaterials for joint repair and replacement.

3. Reed A. Ayers, Evalina Levina Burger, Christopher J. Kleck, and Vikas Patel explore the critical role of metallurgy in designing spinal instrumentation. This chapter focuses on the properties and performance of metals used in spinal implants, examining how their composition and structure affect surgical outcomes.

4. Takeo Matsumoto, Shukei Sugita, and Toshiyuki Yaguchi discuss the biomechanics of blood vessels, analyzing their structural components and mechanical properties. The chapter addresses how these factors contribute to vascular health and how biomaterials can be designed to mimic or restore vessel function.

5. Shinji Kamakura delves into the anatomy and physiology of teeth and their supporting structures, including the periodontal ligament and alveolar bone. This chapter highlights the challenges and innovations in dental biomaterials used for restoration and regeneration.

Part II: Metallic Biomaterials  

The second part focuses on metallic biomaterials, their properties, and their applications in biomedical engineering. These materials are vital for creating implants, prosthetics, and other medical devices due to their strength, durability, and biocompatibility.

6. Yasuyuki Katada and Tetsushi Taguchi explore nickel-free high-nitrogen stainless steel, a revolutionary material designed to reduce allergic reactions while maintaining the strength and corrosion resistance required for biomedical applications. This chapter examines its composition, properties, and potential uses.

7. Takayuki Narushima, Kyosuke Ueda, and Alfirano discuss cobalt-chromium (Co-Cr) alloys, which are widely used in medical implants due to their exceptional strength, wear resistance, and corrosion resistance. This chapter highlights their role in joint replacements, dental implants, and other medical devices.

8. Mitsuo Niinomi and Carl J. Boehlert focus on titanium alloys, renowned for their excellent biocompatibility, lightweight nature, and mechanical strength. The chapter discusses their use in orthopedic implants, dental devices, and other biomedical applications, as well as ongoing research to enhance their properties.

9. Naoyuki introduces zirconium alloys, which have emerged as promising materials for orthopedic implants. This chapter highlights their biocompatibility, resistance to corrosion, and potential to reduce wear in joint replacements.

10. Nilesh Patil and Stuart B. Goodman examine porous tantalum, a material used in orthopedic surgery to reconstruct bone loss. This chapter explores its unique porous structure, which promotes bone in-growth and provides mechanical stability for long-term success.

11. Barry O’Brien presents niobium as an emerging biomaterial with excellent biocompatibility and corrosion resistance. This chapter discusses its applications in dental and orthopedic implants, emphasizing its potential for future medical innovations.

Part III: Reactions of Metals in the Human Body  

The final section addresses the biological interactions of metallic biomaterials once implanted in the human body. These interactions are critical to understanding their long-term performance, safety, and potential complications.

12. Burak Dikici, Ziya Esen, Ozgur Duygulu, and Serap Gungor analyze the corrosion behavior of metallic biomaterials in the human body. This chapter discusses how the physiological environment can affect metal degradation and explores strategies to improve corrosion resistance.

13. Mitsuko Kawano, Yuri Takeda, and Kouetsu Ogasawara investigate allergic reactions to metallic biomaterials. This chapter examines the mechanisms behind metal allergies, their clinical implications, and approaches to designing hypoallergenic materials.

14. Akiko Obata and Toshihiro Kasuga address the cytotoxicity of metallic biomaterials, focusing on how certain metal ions released into the body can affect cell viability. The chapter highlights the importance of material selection and surface treatments to minimize cytotoxic effects.

Through its three parts, this detailed overview bridges the gap between biological systems and engineered materials. By addressing tissue and organ structure, the design of advanced metallic biomaterials, and their interactions with the human body, this comprehensive exploration sheds light on the future of biomedical innovations aimed at improving patient outcomes.

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