Physical Chemistry With Biological Applications By Keith J. Laidler (informative)
Free download Physical Chemistry With Biological Applications By Keith J. Laidler
Authors of: Physical Chemistry With Biological Applications By Keith J. Laidler
Keith J. Laidler
Table of Contents in Physical Chemistry With Biological Applications By Keith J. Laidler
Preface
– Overview of physical chemistry and its significance in understanding biological systems
– Role of physical chemistry in interdisciplinary research
– Structure and objectives of the book
– How to use this book for effective learning
Chapter 1: Introduction to Physical Chemistry
– Definition and scope of physical chemistry
– Importance in biological systems and medicine
– Historical development of physical chemistry
– Key principles that govern chemical and biological reactions
Chapter 2: Atoms, Molecular Structure, and Quantum Chemistry
– Introduction to atomic theory
– Atomic nucleus: protons, neutrons, and electrons
– Electron configurations and their impact on chemical behavior
– Fundamental principles of quantum mechanics
– Wave-particle duality and the Schrödinger equation
– Molecular orbital theory and its applications in biological molecules
– Spectroscopy as a tool to study atomic and molecular structures
Chapter 3: The Periodic Table and Chemical Properties
– Construction of the periodic table
– Periodic trends in atomic and molecular properties
– Electronegativity, ionization energy, and atomic size
– Relationship between the periodic table and biological elements
Chapter 4: Chemical Bonding and Intermolecular Forces
– Types of chemical bonds: covalent, ionic, and metallic
– Hydrogen bonding and van der Waals forces in biological molecules
– The role of non-covalent interactions in protein folding and DNA structure
– Thermodynamics of bond formation and breaking
Chapter 5: Molecular Spectroscopy and Its Biological Applications
– Interaction of electromagnetic radiation with matter
– Ultraviolet-visible (UV-Vis) spectroscopy in protein and nucleic acid analysis
– Infrared (IR) spectroscopy and vibrational transitions
– Nuclear Magnetic Resonance (NMR) spectroscopy in biomolecular structure determination
– Fluorescence spectroscopy in biological imaging
Chapter 6: Thermodynamics and Energy in Biological Systems
– The first law of thermodynamics: energy conservation
– Enthalpy and heat flow in chemical and biological reactions
– The second law of thermodynamics: entropy and spontaneity
– Gibbs free energy and equilibrium in biological processes
– Thermodynamic cycles and bioenergetics
Chapter 7: Chemical Equilibrium and Biological Relevance
– Dynamic equilibrium in chemical reactions
– Le Chatelier’s principle and biological buffers
– Solubility equilibrium and solubility product
– Precipitation and its role in biological and industrial processes
Chapter 8: Chemical Kinetics and Reaction Mechanisms
– The concept of reaction rates
– Rate laws and rate expressions
– Catalysts and enzyme kinetics in biological reactions
– Mechanisms of biological catalysis
– Kinetics of radioactive decay and its medical applications
Chapter 9: Electrochemistry and Redox Reactions
– Oxidation and reduction processes
– Galvanic and electrolytic cells
– Standard reduction potentials and their biological significance
– The role of electrochemistry in nerve impulse transmission
– Corrosion and metal ions in biological systems
– Applications of electrolysis in industrial and medical fields
Chapter 10: Solutions, Mixtures, and Transport Phenomena
– Properties of solutions and their biological significance
– Colligative properties: boiling point elevation and freezing point depression
– Osmotic pressure and its importance in cellular function
– Diffusion and osmosis in biological membranes
– Active transport mechanisms in cells
Chapter 11: Acids, Bases, and Buffers in Biochemical Systems
– Definitions of acids and bases: Arrhenius, Brønsted-Lowry, and Lewis concepts
– pH scale and calculations in biological systems
– Properties and behavior of polyprotic acids
– The role of buffer solutions in maintaining pH homeostasis
– Acid-base titrations and pH curves in laboratory analysis
Chapter 12: Thermodynamics of Biomolecular Interactions
– Ligand binding and receptor interactions
– Enzyme-substrate binding energetics
– Protein-protein and protein-DNA interactions
– Drug binding and pharmacokinetics
Chapter 13: Chemical and Biological Catalysis
– Principles of catalysis in chemical and biological systems
– Mechanisms of enzymatic catalysis
– Industrial applications of biocatalysts
– Computational approaches to enzyme design
Chapter 14: Surface Chemistry and Colloidal Systems
– Adsorption and its biological significance
– Surface tension and micelle formation
– Surfactants in biological and industrial processes
– Applications in drug delivery and nanotechnology
Chapter 15: Photochemistry and Light-Induced Processes
– Basic principles of photochemistry
– Photosynthesis: Light-harvesting and electron transport chain
– Role of photochemistry in vision and bioluminescence
– Applications in photodynamic therapy and bioimaging
Chapter 16: Macromolecular Structure and Function
– Structure and dynamics of proteins, nucleic acids, and polysaccharides
– Principles of macromolecular assembly
– Role of non-covalent interactions in biological structures
Chapter 17: Statistical Mechanics and Molecular Biology
– Molecular distributions and energy states
– Relationship between entropy and molecular motion
– Applications of statistical mechanics in protein folding and ligand binding
Chapter 18: Biophysical Techniques in Chemical and Biological Research
– X-ray crystallography for protein and nucleic acid structure
– Electron microscopy techniques
– Molecular modeling and computational chemistry
Chapter 19: Computational Chemistry in Biochemical Research
– Molecular dynamics simulations of biomolecules
– Quantum chemistry approaches to biological problems
– Predictive modeling in drug design
Chapter 20: Chemical Evolution and the Origin of Life
– Prebiotic chemistry and the emergence of biomolecules
– Hypotheses on the origin of life
– Role of physical chemistry in understanding abiogenesis
Appendices
– Mathematical tools and formulas for physical chemistry
– Physical constants and reference tables
– Glossary of key terms in physical and biological chemistry
Index
This expanded table of contents provides a detailed roadmap for the book, covering all essential topics in physical chemistry while emphasizing their applications in biological systems. The integration of thermodynamics, kinetics, spectroscopy, electrochemistry, and molecular modeling ensures a comprehensive resource for students and professionals in chemistry, biology, and related fields.
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