Free Download Modern Methods of Organic Synthesis By William Carruthers And Iain Coldham – 4th Edition

Modern Methods of Organic Synthesis By William Carruthers And Iain Coldham

Authors:
William Carruthers
Formerly of the University of Exeter
Iain Coldham
University of Sheffield

Table of Contents

Preface to the first edition page

Preface to the fourth edition

1 Formation of carbon-carbon single bonds

1.1 Main-group chemistry

1.1.1 Alkylation of enolates and enamines

1.1.2 Conjugate addition reactions of enolates and enamines

1.1.3 The aldol reaction

1.1.4 Asymmetric methodology with enolates and enamines

1.1.5 Organolithium reagents

1.1.6 Organomagnesium reagents

1.1.7 Organozinc reagents

1.1.8 Allylic organometallics of boron, silicon and tin

1.2 Transition-metal chemistry

1.2.1 Organocopper reagents

1.2.2 Organochromium chemistry

1.2.3 Organocobalt chemistry

1.2.4 Organopalladium chemistry

2 Formation of carbon-carbon double bonds

2.1 _-Elimination reactions

2.2 Pyrolytic syn eliminations

2.3 Fragmentation reactions

2.4 Alkenes from hydrazones

2.5 Alkenes from1,2-diols

2.6 Alkenes from alkynes

2.7 The Wittig and related reactions

2.8 Alkenes from sulfones

2.9 Alkenes using titanium or chromium reagents

2.10 Alkene metathesis reactions

3 Pericyclic reactions

3.1 The Diels–Alder cycloaddition reaction

3.1.1 The dienophile

3.1.2 The diene

3.1.3 Regiochemistry of the Diels–Alder reaction

3.1.4 Stereochemistry of the Diels–Alder reaction

3.1.5 Intramolecular Diels–Alder reactions

3.1.6 The retro Diels–Alder reaction

3.1.7 Asymmetric Diels–Alder reactions

3.2 [2+2] Cycloaddition reactions

3.3 Cycloaddition reactions with allyl cations and allyl anions

3.4 1,3-Dipolar cycloaddition reactions

3.5 The ene reaction

3.6 [3,3]-Sigmatropic rearrangements

3.6.1 The Cope rearrangement

3.6.2 The Claisen rearrangement

3.7 [2,3]-Sigmatropic rearrangements

3.8 Electrocyclic reactions

Problems

4 Radical and carbene chemistry

4.1 Radicals

4.1.1 Radical abstraction reactions

4.1.2 Radical addition reactions

4.2 Carbenes

5 Functionalization of alkenes

5.1 Hydroboration

5.1.1 Reactions of organoboranes

5.2 Epoxidation and aziridination

5.2.1 Epoxidation

5.2.2 Asymmetric epoxidation

5.2.3 Aziridination

5.3 Dihydroxylation

5.3.1 Dihydroxylation with osmium tetroxide

5.3.2 Other methods of dihydroxylation

5.3.3 Amino-hydroxylation

5.4 Oxidative cleavage

5.5 Palladium-catalysed oxidation of alkenes  

6 Oxidation

6.1 Oxidation of hydrocarbons

6.1.1 Alkanes

6.1.2 Aromatic hydrocarbons

6.1.3 Alkenes

6.2 Oxidation of alcohol

6.2.1 Chromium reagents

6.2.2 Oxidation via alkoxy-sulfonium salts

6.2.3 Manganese reagents

6.2.4 Other metal-based oxidants

6.2.5 Other non-metal-based oxidants

6.2.6 Oxidation of carboxylic acids or esters

6.3 Oxidation of ketones

6.3.1 _,_-Unsaturated ketones

6.3.2 _-Hydroxy-ketones

6.3.3 Baeyer–Villiger oxidation of ketones

7 Reduction

7.1 Catalytic hydrogenation

7.2 Reduction by dissolving metals

7.3 Reduction by hydride-transfer reagents

7.3.3 Derivatives of lithium aluminum hydride and sodium borohydride

7.3.4 Mixed lithium aluminum hydride–aluminum chloride reagents

7.3.5 Diisobutylaluminium hydride (DIBAL-H)

7.3.6 Sodium cyanoborohydride and sodium triacetoxyborohydride

7.3.7 Borane and derivatives

7.4 Other methods of reduction

7.4.1 Enzyme catalyzed

7.4.2 Wolff–Kishner reduction

7.4.3 Reductions with diimide

7.4.4 Reductions with trialkyl-silanes

Problems

Answers to problems

Index

Free download Modern Methods of Organic Synthesis By William Carruthers And Iain Coldham in pdf from the following download links.

File Size: 6.64 MB. Pages: 507. Please read Disclaimer.

Download Link 1

You may also like “Organic Chemistry Second Edition by Jonathan Clayden, Nick Greeves, and Stuart Warren”.

You can also buy Modern Methods of Organic Synthesis By William Carruthers And Iain Coldham from Amazon by Clicking the image below

Free download hundreds of chemistry books in pdf from HERE.

Please Subscribe to our Email list and get notified of our latest uploads (Books, documents) and new updates. Email Subscription Box is provided on the sidebar (for PC) and on the bottom of this post (for Android Devices).

Kindly Like, Follow and Share our social media pages so that maximum people can get the benefit from this public service!

Facebook   Instagram    LinkedIn    Twitter    Pinterest

P.S: If the download link(s) is/are not working, kindly drop a comment below, so we’ll update the download link for you.

Happy reading!